You can ask about her background, life in general and tips on getting the most out of Thailand.
Phuket sex guide
Once you start talking, things usually progress in a friendly and positive manner.
If you discover anything suspicious, rather back off and leave her alone.
In fact, the ladyboy population is so vast that there the opportunity the transgender community. Remember that this bus only operates from 6am to 6pm, so long nights on the beach should be planned with alternative transport in mind.